Researchers examined sex differences in the prevalence and development of CKD – a study review by the BIOMEDICA CRO team
Chronic Kidney Disease (CKD) affects about 10% of the population annually. Scientists from Karolinska Institutet in Sweden discovered that women with reduced kidney function received a diagnosis of CKD less than men in the same situation.
“Our results clearly show sex differences in the care of Chronic Kidney Disease that disadvantage women. We believe that efforts to improve the situation and ensure equal care can reduce both society’s and the individual’s burden of this disease”, – Juan Jesus Carrero, study’s last author, professor at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet.
Researchers recruited over 220,000 people 18+ years identified when they first exhibited reduced kidney function with a so-called eGFR value below 60 ml/min/1.73m2.
In 91 percent of the men and 87 percent of the women, kidney function had been monitored by additional creatinine measurement at least once over the subsequent 18 months. The numbers for the measurement of albumin in the urine were lower: 34 percent and 28 percent, respectively. The differences between men and women were attenuated but remained when the researchers adjusted for comorbidities, medications or educational level and were also noticed among people with confirmed Chronic Kidney Disease after repeated testing.
Mentioned above results bring attention to a problem amenable to correction, and this should be the next focus.
Please find more information in the Journal of the American Society of Nephrology, “Sex Differences in the Recognition, Monitoring, and Management of CKD in Health Care: An Observational Cohort Study”.
Chronic Kidney Disease biospecimens collection for your research by BIOMEDICA CRO
BIOMEDICA CRO has provided prospective and retrospective collections of the numerous human biospecimen types and associated clinical data since 2017.
We built a strong base of clinical sites with 50+ contracted hospitals in various disease areas. The access to nephrology departments allows us to provide biospecimens from donors with Chronic Kidney Disease for your research.
It is feasible to collect the following specimens from this cohort:
- Whole blood;
- Single/double spun plasma;
- Serum;
- Buffy coat;
- PBMCs;
- Urine;
- Stool;
- Saliva, etc.
In addition to human biospecimens, we can obtain precise clinical data, laboratory test results and other valuable information from each donor.
Please email us to start our collaboration: office@biomedica-cro.com / LinkedIn. Our professional team is ready to join new projects and contribute to scientific cooperation!
