Check out the latest scientific article review by the BIOMEDICA CRO team, highlighting new targets for the treatment of Psoriasis
Researchers recently carried out a transcriptome-wide association study (TWAS) to gain insight into the genetic origins of Psoriasis, a skin condition characterized by chronic inflammation.
The results from the TWAS analysis identified 101 genes exhibiting significant associations in the single-tissue panels, while the multi-tissue panels identified 64 genes. Of these, 26 genes showed similar significant associations in the COLOC analysis.
Furthermore, through conditional and joint analysis, certain drugs were identified as potential candidates demonstrating interactions with significant genes.
Overall, the findings reported 26 potential genetic markers for Psoriasis that were identified using multiple methods such as TWAS and COLOC and whose functional association with immune responses and Psoriasis was validated using network analysis and functional annotation.
Please find more information in the MDPI journal, article “A Transcriptome-Wide Analysis of Psoriasis: Identifying the Potential Causal Genes and Drug Candidates”.
BIOMEDICA CRO team collects biospecimens & associated data while YOUR focus is on dermatological diseases research
BIOMEDICA CRO has provided prospective and retrospective collections of the numerous human biospecimen types and associated clinical data since 2017.
We manage our own network of 50+ direct contracts with hospitals in many therapeutic areas and are ready to make a new one if necessary. The access to therapy departments allows us to supply biospecimens from healthy donors and, for example, subjects with dermatological conditions such as:
• Psoriasis;
• Atopic Dermatitis;
• Eczema;
• Acne;
• Lichen Planus;
• Healthy control group – smokers/non-smokers, age-gender-BMI matched to diseased patients, etc.
🩸 In addition to human biospecimens, we can provide precise clinical data, laboratory test results and other valuable information from each donor to cover your research needs.
Our main focus is on a prospective collection of human biospecimens, however we also offer a diverse selection of ready-to-ship biosamples from our Inventory obtained from subjects with Psoriasis and other dermatological diseases.
BIOMEDICA CRO team takes pride in contributing to preclinical trials, in-vitro diagnostics and drug discovery. Should you require the services of an additional supplier of biospecimens for your research, we would be more than happy to cooperate!
📩 Please email us to start our collaboration at office@biomedica-cro.com / LinkedIn. We can fight numerous diseases and improve human life by working together!
