Researchers reveal how bacteria infiltrate tumors and could be helping tumors progress and spread – the latest research article review by BIOMEDICA CRO team
Two new studies from researchers at Fred Hutchinson Cancer Center in Seattle reveal how bacteria infiltrate tumors and could be helping tumors progress and spread. The research team also showed that the different microbial players in a tumor’s microbiome could influence how cancer responds to treatment.
The findings also suggest a link between oral health and cancer, as microbes in the mouth are associated with cancers elsewhere in the body.
“This work is at the intersection of cancer and microbiome research. There’s compelling emerging data to suggest that nearly all major cancer types harbor an intra-tumoral microbiota.”, – Susan Bullman, PhD, Fred Hutch cancer microbiome researcher. An association with bacteria may seem logical in colorectal cancer, but breast, pancreatic and lung tumors are among other cancers shown to harbor microbial communities, and studies are showing that tumor microbiomes may shape development, progression and response to treatment.
“This holistic approach to assessing the tumor microenvironment, which is a multi-species ecosystem, will advance our understanding of cancer biology, and I believe will reveal new therapeutic vulnerabilities in cancer,” Bullman said.
Please find more information on the Fred Hutch Cancer Center website, news, “How bacteria give cancer a helping hand”.
The contribution of BIOMEDICA CRO in preclinical studies directed to cancer research
At BIOMEDICA CRO we routinely collect hundreds of human biospecimens with valuable and precise clinical data for pharmaceutical companies and diagnostic centers worldwide.
We manage our own network of 50+ direct contracts with hospitals in Ukraine in many disease areas and are always ready to make a new one if necessary. Our main area is oncology and the study of the following conditions:
• Breast cancer;
• Colorectal Cancer;
• Prostate Cancer;
• Kidney Cancer;
• Endometrial cancer,
• Head & Neck cancer, etc.
It is feasible to collect tissue samples (tumor/NAT FFPE blocks, fresh frozen tissue samples, histological slides, and lymph nodes), blood samples (plasma, serum, buffy coat, PBMC) and other biofluids from this cohort.
All human biospecimens we provide are collected under the internal company SOPs, as well as with your particular recommendations. Our experienced study managers bring all project steps in sync with your unique needs.
Once you are close to conducting preclinical trials, we are ready to provide full support in line with good laboratory (GLP) and good clinical practices (GCP).
Please email us to start our collaboration at office@biomedica-cro.com / LinkedIn.
