Acetylsalicylic acid (aspirin) in cancer treatment – the latest research article review by BIOMEDICA CRO team
In a recent review published in Open Biology, researchers discussed the existing evidence on the use of acetylsalicylic acid (aspirin) in cancer treatment.
Studies on metastasis using in vivo animal models and in vitro cell lines have shown that platelets play a significant role in enabling metastatic migration by secreting growth factors, promoting metastatic niche formation, and producing inhibitors of tumor suppressor genes.
According to the authors, many studies have focused on common cancers such as Lung, Breast, Prostate, and Colon cancer, that account for only 30% of the worldwide cancer cases, leaving the rarer forms of cancer understudied.
There appears to be an impressive harmony between the biological effects of aspirin on mechanisms relevant to cancer, and the effects of aspirin on clinical outcomes in cancer. Furthermore, additional research is needed on the use of aspirin in the treatment of some of the rarer forms of cancer.
Please find more information on the Royal Society website, articles, “Aspirin and cancer: biological mechanisms and clinical outcomes”.
Human biological samples collection for in vitro studies by BIOMEDICA CRO – trusted provider since 2017
At BIOMEDICA CRO we have collected various human biospecimens and associated clinical data in a wide range of disease areas since 2017.
For instance, we have good access to donors with oncological conditions, such as:
• Breast cancer;
• Colorectal Cancer;
• Prostate Cancer;
• Kidney Cancer;
• Cervical cancer, etc.
It is feasible to collect tissue samples (tumor/NAT FFPE blocks, fresh frozen tissue samples, histological slides, and lymph nodes), blood samples (plasma, serum, buffy coat, PBMC) and other biofluids from this cohort.
Once you are close to conducting pre-clinical trials, we are ready to provide full support in line with good laboratory (GLP) and good clinical practices (GCP).
Please email us to start our collaboration at office@biomedica-cro.com / LinkedIn.
